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Very slightly soluble in water, slightly soluble in acetone and in ethanol
Storage
Keep in dark place,Sealed in dry,Room Temperature
Complicated and uncomplicated urinary tract infections (including prophylaxis in recurrent infections), prostatitis,Uncomplicated gonorrhea,Gastroenteritis caused by Salmonella, Shigella and Campylobacter spp., Vibrio cholerae and Conjunctivitis (ophthalmic preparation)Norfloxacin belongs to third-generation quinolone antibacterial agent developed by Japanese Kyorin Company in 1978. It has features of broad antibacterial spectrum and strong antibacterial activity. It has a strong antibacterial effect against Escherichia coli, pneumobacillus, Aerobacter aerogenes, and Aerobacter cloacae, Proteus, Salmonella, Shigella, Citrobacter and Serratia. It is clinically used for treating the susceptible strain’s causing infections of urinary system, intestinal, respiratory system, surgery, gynecology, ENT and dermatology. It can also be used for the treatment of gonorrhea.Norfloxacin is a quinolone-class anti-infective drug with high degree of antibacterial activity against Escherichia coli, Shigella, Salmonella, Proteus, Pseudomonas aeruginosa and other gram-negative bacteria as well as excellent antibacterial effect against Staphylococcus aureus, pneumococcus bacteria and other Gram-positive bacteria. Its major site of action is in the bacterial DNA gyrase, causing the rapid cracking of the bacteria DNA helix and rapidly inhibiting the bacterial growth and reproduction, finally killing the bacteria. Moreover, it has a strong penetration capability into the cell walls so that it has a stronger bactericidal effect with a small stimulation on the gastric mucosa. Norfloxacin is a synthetic chemotherapeutic agent occasionally used to treat common as well as complicated urinary tract infections.