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Potassium bicarbonate is water soluble alkaline potassium salt with monoclinic crystalline structure. It is a raw material for the synthesis of many potassium compounds. It is a better coolant than sodium bicarbonate in the aerosol fire extinguishing apparatus. It shows potential as an antifungal agent.Sodium bicarbonate and potassium bicarbonate are key components of body tissues that help regulate the body’s acid or base balance. This formula of buffered mineral compounds can assist in reestablishing the acid or base balance when the body’s own bicarbonate reserves are depleted because of metabolic acidosis caused by adverse reactions to food or other environmental exposures. Potassium is excellent for heart health, If a person does not have enough potassium in the body, a condition known as hypokalemia, negative symptoms can occur. These include fatigue, muscle cramping, constipation, bloating, muscle paralysis and potentially life-threatening heart rhythms, according to the Linus Pauling Institute. Taking potassium bicarbonate can help to reduce these symptoms. Potassium bicarbonate also can lower blood pressure and reduce the risk of developing kidney stones.As an excipient, potassium bicarbonate is generally used in formulations as a source of carbon dioxide in effervescent preparations, at concentrations of 25–50% w/w. It is of particular use in formulations where sodium bicarbonate is unsuitable, for example, when the presence of sodium ions in a formulation needs to be limited or is undesirable. Potassium bicarbonate is often formulated with citric acid or tartaric acid in effervescent tablets or granules; on contact with water, carbon dioxide is released through chemical reaction, and the product disintegrates. On occasion, the presence of potassium bicarbonate alone may be sufficient in tablet formulations, as reaction with gastric acid can be sufficient to cause effervescence and product disintegration. Potassium bicarbonate is also used in food applications as an alkali and a leavening agent, and is a component of baking powder. Therapeutically, potassium bicarbonate is used as an alternative to sodium bicarbonate in the treatment of certain types of metabolic acidosis. It is also used as an antacid to neutralize acid secretions in the gastrointestinal tract and as a potassium supplement.
